PuSH - Publication Server of Helmholtz Zentrum München: Retrovirus-induced osteopetrosis in mice : Ultrastructural evidence of early virus production in osteoblasts and osteocytes.

Navigation

Home

Deutsch

Research

Advanced Search

Browse by ...

... Journal

... Publication Type

... Research Data

... Publication Year

Publication overview

Support & Contact

Contact persons

Help

Data protection

Murray, A.B. ; Schmid, J. ; Rieke, L.

Retrovirus-induced osteopetrosis in mice : Ultrastructural evidence of early virus production in osteoblasts and osteocytes.

Am. J. Pathol. 124, 319-323 (1986)

DOI

PMC

Open Access Green as soon as Postprint is submitted to ZB.

Abstract
Metrics
Extra information

Newborn female strain NMRI mice were given injections of a mouse retrovirus (OA MuLV) known to induce osteopetrosis, osteoma, and lymphoma. Femur metaphyses and lumbar vertebrae were investigated ultrastructurally 3 d, 7 d and 28 d after infection. Budding, immature and mature virus was observed associated with osteoblasts and osteocytes, but not with osteoclasts or chondrocytes, 28 d after infection with the virus. No production of virus particles was observed in bone-tissue in mock-treated controls. Thus, the primary target cell for OA virus in bone appears to belong to the osteoblastic/osteocytic cell lineage.

Altmetric

Additional Metrics?

[➜Log in]

Edit extra informations Login

Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

ISSN (print) / ISBN 0002-9440

e-ISSN 1525-2191

Journal American Journal of Pathology, The

Quellenangaben Volume: 124, Issue: 2, Pages: 319-323

Publisher Elsevier

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Pathology (PATH)