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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Cholestyramine enhances fecal elimination of pentachlorophenol in rhesus monkeys.
Chemosphere 10, 877-888 (1981)
The effect of cholestyramine in the daily diet upon the excretion of pentachlorophenol with the feces was studied in the rhesus monkey. The treatment increased fecal elimination of pentachlorophenol and/or metabolites up to 9- to 14-fold over a six-day period. At the same time urinary excretion was reduced 2- to 6-fold. The data suggest that cholestyramine interrupts the enterhepatic circulation of PCP and/or metabolites thus indicating its possible usefulness in preventing toxicity of PCP that otherwise may occur due to reabsorption of biliary PCP and/or metabolites.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0045-6535
e-ISSN
1879-1298
Journal
Chemosphere
Quellenangaben
Volume: 10,
Issue: 8,
Pages: 877-888
Publisher
Elsevier
Publishing Place
Kidlington, Oxford
Reviewing status
Peer reviewed
Institute(s)
Institute of Ecological Chemistry (IOEC)