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Open Access Green as soon as Postprint is submitted to ZB.
Repair of DNA double-strand breaks in irradiated yeast cells under nongrowth conditions.
Radiat. Res. 82, 498-510 (1980)
Publ. Version/Full Text
DOI
We show that in diploid yeast radiation-induced DNA double-strand breaks can be repaired under nongrowth conditions at 30°C and that liquid holding recovery of colony-forming ability is accompanied by a decrease in the number of double-strand breaks per cell. The kinetics of double-strand break repair under nongrowth conditions depend on the dose applied. For the highest dose used (2400 Gy) repair is completed within about 48 hr. We have verified that double-strand breaks which remain unrepaired after 48 hr are irreparable under nongrowth conditions. The linear relationship between the initial number of double-strand breaks and dose is converted into a quadratic function of irreparable double-strand breaks with and dose during liquid holding treatment of cells.
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Publication type
Other: Correction, Addition
ISSN (print) / ISBN
0033-7587
e-ISSN
1938-5404
Journal
Radiation Research
Quellenangaben
Volume: 82,
Issue: 3,
Pages: 498-510
Publisher
Radiation Research Society
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Abteilung Biophysikalische Strahlenforschung