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Trott, K.R.* ; Lieven, H.V.* ; Kummermehr, J.C. ; Skopal, D.* ; Lukacs, S.* ; Braun-Falco, O.*

The radiosensitivity of malignant melanomas part I: Experimental studies.

Int. J. Radiat. Oncol. Biol. Phys. 7, 9-13 (1981)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Human and hamster malanoma cells were irradiated is vitro with single and fractionated daces of γ-rays. Except for a tendency to high extrapolation numbers, survival curves did not show particular radioresistance. D2-D1 was between 220 and 300 rad. Regrowth delay after split dose irradiation to the hypoxic Hardiog-Passey malanoma in vivo yielded a D2-D, of 700 rad. While the tumor control dose for 50% (TCD-50) was within normal range (4,400 rad) Harding-Passey malanom as regressed very slowly after irradiation and often took months to clear away.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Melanoma Cells ; Split Dose Recovery ; Tumor Regression
ISSN (print) / ISBN 0360-3016
e-ISSN 0360-3016
Journal International Journal of Radiation Oncology, Biology, Physics
Quellenangaben Volume: 7, Issue: 1, Pages: 9-13 Article Number: , Supplement: ,
Publisher Elsevier
Reviewing status Peer reviewed
Institute(s) Departments & Institutes