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Long-term exposure of dogs to a sulphite aerosol: III. Effect of lung clearance.
J. Aerosol Sci. 21, S479-S482 (1990)
Eight dogs were exposed to a sodium bisulphite aerosol during 290 days. Lung clearance was tested with moderately soluble and insoluble aerosol particles after a single inhalation. Three dogs showed significant changes in clearance rate of moderately soluble particles during the sulphite exposure compared to the clearance rate during clean air exposure. The results were confirmed by in vitro clearance measurements in alveolar macrophages.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Chronio Exposure ; Clearance Mechanism ; Dog ; Lung ; Lung Retention ; Mechanical Particle Transport, Translocation, Intracellular Particle Dissolution ; Sulphite Aerosol
Language
english
Publication Year
1990
HGF-reported in Year
0
ISSN (print) / ISBN
0021-8502
e-ISSN
1879-1964
Journal
Journal of Aerosol Science
Quellenangaben
Volume: 21,
Issue: SUPPL. 1,
Pages: S479-S482
Publisher
Elsevier
Reviewing status
Peer reviewed
Institute(s)
Institute of Radiation Protection (ISS)
Scopus ID
0025640528
Erfassungsdatum
1990-12-31