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Distribution and bioconcentration potential of the environmental chemical pentachlorophenol (PCP) in different tissues of humans.

Chemosphere 16, 887-899 (1987)
DOI
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The bioconcentration factors (BCFs) of pentachlorophenol (PCP) in different tissues, organs and body fluids of humans were calculated by two methods: 1) from daily intake of PCP and its measured concentrations in different tissues and, 2) from measured half-life and measured PCP concentrations in the human body at steady state using a linear one compartment pharmacokinetic model. The BCFs (based on wet weight) in liver, brain, blood, spleen and adipose tissue of humans as calculated by method 1 were 5.7, 3.3, 1.4, 1.4, and 1.0, respectively. The figures obtained by method 2 were in good agreement to those obtained by method 1.
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 0045-6535
e-ISSN 1879-1298
Journal Chemosphere
Quellenangaben Volume: 16, Issue: 4, Pages: 887-899 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Kidlington, Oxford
Reviewing status Peer reviewed
Institute(s) Institute of Ecological Chemistry (IOEC)