Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
Publ. Version/Full Text
DOI
PMC
 |
Licenced for HMGU |
Open Access Green as soon as Postprint is submitted to ZB.
Effect of dose rate on the induction of DNA double-strand breaks in eukaryotic cells.
Radiat. Res. 87, 710-717 (1981)
Publ. Version/Full Text
DOI
PMC
Irradiation of diploid yeast cells with 30-MeV electrons at a high dose rate (130 Gy/min) was previously shown to yield a linear-quadratic function between irreparable double-strand breaks and dose. The quadratic term is reduced when irradiation is performed with 60Co γ rays at a low dose rate (0.55 Gy/min). This effect of dose rate at the level of double-strand breaks correlates with that previously found at the level of colony-forming ability of yeast cells irradiated in the same dose range. By analogy with the results obtained in survival studies it is proposed that the linear component of the relationship between irreparable double-strand breaks and dose is due to a single track of an electron of medium energy, whereas the quadratic component is caused by the cooperative effect of track ends, each of which is produced by a separate traversal of a slow electron through the yeast nucleus.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0033-7587
e-ISSN
1938-5404
Journal
Radiation Research
Quellenangaben
Volume: 87,
Issue: 3,
Pages: 710-717
Publisher
Radiation Research Society
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Abteilung Biophysikalische Strahlenforschung