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Hagen, U.

Genetische Wirkungen kleiner Stahlen-Dosen.

Genetic effect of low doses of lonizing radiation.

Naturwissenschaften 74, 3-11 (1987)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
There are several approaches to evaluate the genetic effects of low doses of ionizing radiation in a human population. Based on experiments on mice using high doses, the genetic risk for humans has to be derived by extrapolation to low doses, assuming mouse and man respond in a similar way. Microdosimetric considerations indicate a linear relationship; studies on the molecular mechanism of radiation-induced mutagenesis lead to the conclusion that, in addition to a constitutive mutagenic process, an inducible compound exists which may cause linear-quadratic dose-effect curves. Linear extrapolation seems thus to be justified; however, the genetic risk of low doses may be slightly overestimated.
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Publication type Article: Journal article
Document type Scientific Article
Language german
Publication Year 1987
HGF-reported in Year 0
ISSN (print) / ISBN 0028-1042
e-ISSN 1432-1904
Journal Naturwissenschaften, Die
Quellenangaben Volume: 74, Issue: 1, Pages: 3-11 Article Number: , Supplement: ,
Publisher Springer
Reviewing status Peer reviewed
Institute(s) Institute of Radiation Biology (ISB)
PubMed ID 3561515
DOI 10.1007/BF00367034
Scopus ID 0023154487
Erfassungsdatum 1987-12-31
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