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Open Access Green as soon as Postprint is submitted to ZB.
Genetische Wirkungen kleiner Stahlen-Dosen.
Genetic effect of low doses of lonizing radiation.
Naturwissenschaften 74, 3-11 (1987)
There are several approaches to evaluate the genetic effects of low doses of ionizing radiation in a human population. Based on experiments on mice using high doses, the genetic risk for humans has to be derived by extrapolation to low doses, assuming mouse and man respond in a similar way. Microdosimetric considerations indicate a linear relationship; studies on the molecular mechanism of radiation-induced mutagenesis lead to the conclusion that, in addition to a constitutive mutagenic process, an inducible compound exists which may cause linear-quadratic dose-effect curves. Linear extrapolation seems thus to be justified; however, the genetic risk of low doses may be slightly overestimated.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0028-1042
e-ISSN
1432-1904
Journal
Naturwissenschaften, Die
Quellenangaben
Volume: 74,
Issue: 1,
Pages: 3-11
Publisher
Springer
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Radiation Biology (ISB)