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Lauk, S. ; Kiszel, Z. ; Buschmann, J. ; Trott, K.R.

Radiation-induced heart disease in rats.

Int. J. Radiat. Oncol. Biol. Phys. 11, 801-808 (1985)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
After local irradiation of the rat heart with X ray doses of over 10 Gy (single doses), animals developed symptoms of radiation-induced heart disease, which at higher doses would lead to fatal cardiac failure. The LD 50 at 1 year was between 15 Gy and 20 Gy. The pericardium and epicardium responded to irradiation with exudative pericarditis after 4 months. Focal myocardial damage was secondary to progressive capillary damage.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Chronic radiation damage; Heart; Capillaries
Language english
Publication Year 1985
HGF-reported in Year 0
ISSN (print) / ISBN 0360-3016
e-ISSN 0360-3016
Journal International Journal of Radiation Oncology, Biology, Physics
Quellenangaben Volume: 11, Issue: 4, Pages: 801-808 Article Number: , Supplement: ,
Publisher Elsevier
Reviewing status Peer reviewed
Institute(s) Abteilung für Strahlenbiologie und Biophysik
PubMed ID 3980275
DOI 10.1016/0360-3016(85)90314-1
Scopus ID 0021884444
Erfassungsdatum 1985-04-30
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