PuSH - Publication Server of Helmholtz Zentrum München

Herbert, A.* ; Gerry, N.P.* ; McQueen, M.B.* ; Heid, I.M. ; Pfeufer, A. ; Illig, T. ; Wichmann, H.-E. ; Meitinger, T. ; Hunter, D.* ; Hu, F.B.* ; Colditz, G.* ; Hinney, A.* ; Hebebrand, J.* ; Koberwitz, K. ; Zhu, X.F.* ; Cooper, R.* ; Ardlie, K.* ; Lyon, H.* ; Hirschhorn, J.N.* ; Laird, N.M.* ; Lenburg, M.E.* ; Lange, C.* ; Christman, M.F.*

Response to Comments on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity".

Science 315, 187e (2007)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Identification of genetic variants affecting complex traits such as obesity is confounded by many types of bias, especially when effect sizes are small. Given our findings of a positive association between rs7566605 and body mass index in four out of five separate samples, a false positive finding cannot be ruled out with certainty but seems unlikely. Meta-analyses of multiple large studies will help refine the estimate of the effects of rs7566605 on body mass index.
Altmetric
Additional Metrics?
[➜Log in]
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0036-8075
e-ISSN 1095-9203
Journal Science
Quellenangaben Volume: 315, Issue: 5809, Pages: 187e Article Number: , Supplement: ,
Publisher American Association for the Advancement of Science (AAAS)
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)