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Iliakis, G.E.

The mutagenicity of alpha particles in Ehrlich ascites tumor cells.

Radiat. Res. 99, 52-58 (1984)
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Open Access Green as soon as Postprint is submitted to ZB.
Cell killing and the induction of mutation to thioguanine resistance (HGPRT enzyme deficiency) were measured after exposure of Ehrlich ascites tumor cells to 150-kV X rays and 241Am α particles. The curve describing the induction of mutations was almost linear after exposure to α particles (slope: 14.1 x 10-5 Gy-1) but upward bending after exposure to X rays, apparently reaching a final slope similar to that obtained after exposure to α particles. The number of mutants induced per viable cell by α particles at a given level of cell killing was similar to that induced by X rays. The RBE values obtained for cell killing and the induction of mutations are compared with each other, and the possible involvement of repair processes in determining the RBE is discussed.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 1984
HGF-reported in Year 0
ISSN (print) / ISBN 0033-7587
e-ISSN 1938-5404
Journal Radiation Research
Quellenangaben Volume: 99, Issue: 1, Pages: 52-58 Article Number: , Supplement: ,
Publisher Radiation Research Society
Reviewing status Peer reviewed
Institute(s) Abteilung Biophysikalische Strahlenforschung
Scopus ID 0021244485
Erfassungsdatum 1984-12-31
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