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Open Access Green as soon as Postprint is submitted to ZB.
Calculation of the dose-rate dependence of the dicentric yield after co γ-irradiation of human lymphocytes.
Int. J. Radiat. Biol. 35, 229-233 (1979)
The dose relation for dicentrics after in vitro Co γirradiation of human lymphocytes with dose rates of 50 and 1·7 rad/min fit the linear-quadratic function y = αD + βD2. Compared with 50 rad/min, after 1·7 rad/min αD was unchanged, whereas βD2 was decreased by 36 per cent. By applying the mean interaction time t̃ ≈ 110 min for primary breaks, determined in an earlier experiment, and Lea's G-function, a theoretical dose relation for 1·7 rad/min can be calculated from the dose relation of the higher dose rate. This theoretical function is not significantly different from the corresponding experimental curve. Thus, from calibration curves with conventional dose rates dose-effect curves for low dose rates can be derived without the need for time-consuming chromosome analyses.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Quellenangaben
Volume: 35,
Issue: 3,
Pages: 229-233
Publisher
Informa Healthcare
Reviewing status
Peer reviewed
Institute(s)
Institut für Biologie