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Frankenberg, D. ; Frankenberg-Schwager, M.

Interpretation of the shoulder of dose-response curves with immediate plating in terms of repair of potentially lethal lesions during a restricted time period.

Int. J. Radiat. Biol. 39, 617-631 (1981)

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Open Access Green as soon as Postprint is submitted to ZB.

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It is shown theoretically that a shouldered dose-response curve may be obtained when repair of Poisson-distributed potentially lethal lesions occurs during a restricted time period between plating irradiated cells on nutrient agar and fixation of potentially lethal lesions. This interpretation is supported by experiments showing that an increased shoulder width of the dose-response curve is observed when irradiated cells are given more time for repair of potentially lethal lesions.

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Publication type Article: Journal article

Document type Scientific Article

ISSN (print) / ISBN 0955-3002

e-ISSN 1362-3095

Journal International Journal of Radiation Biology

Quellenangaben Volume: 39, Issue: 6, Pages: 617-631

Publisher Informa Healthcare

Reviewing status Peer reviewed

Institute(s) Abteilung Biophysikalische Strahlenforschung