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The octanol/water distribution of mercury compounds.
Arch. Toxicol. 57, 139-141 (1985)
Lipophilicity plays an important role in the biological action of mercurials. The distribution of one inorganic and five organic mercury compounds was determined in an n-octanol/water system. Lipophilicity decreased in the order CH3HgCl, bromomercurihydroxypropane, HgCl2, chlormerodrin, p-chloromercuribenzoic acid (PCMB), p-chloromercuriphenylsulfonic acid (PCMBS). The toxicity of mercurials, as reported in the literature, appears to parallel their lipophilicity.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0340-5761
e-ISSN
1432-0738
Journal
Archives of Toxicology
Quellenangaben
Volume: 57,
Issue: 2,
Pages: 139-141
Publisher
Springer
Reviewing status
Peer reviewed
Institute(s)
Institut für Toxikologie und Biochemie