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Variation of mutation and recombination frequencies over a range of thymidylate concentrations in a diploid thymidylate auxotroph.

Curr. Genet. 7, 399-402 (1983)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
A diploid yeast thymidylate auxotroph was grown under conditions of thymidylate stress ranging from depletion to excess levels of the nucleotide. High concentrations of thymidylate were mutagenic and recombinagenic whereas starvation for thymine nucleotides was recombinagenic and only slightly mutagenic. These results are discussed in relation to possible mutagenic and recombinagenic mechanisms of nucleotide pool imbalances.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0172-8083
e-ISSN 1432-0983
Quellenangaben Volume: 7, Issue: 5, Pages: 399-402 Article Number: , Supplement: ,
Publisher Springer
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Abteilung für Strahlenbiologie und Biophysik