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Studies on short-lived internal αemitters in mice and rats: Part i. 224ra.
Int. J. Radiat. Biol. 20, 27-38 (1971)
The distribution of intraperitonally-injected 224Ra was studied in NMRI mice and WISTAR rats. The highest activity concentrations were found in the skeleton. High radium concentrations were also obtained in the spleen (in mice higher than in rats, increasing with age). The calculated values were 12 rads/day for initial skeletal dose-rate and 30 rads for total averaged skeletal dose by supporting 1 μCi/kg 224Ra. The dose relationships of the short-lived 224Ra were contrasted to those of the long-lived 226Ra. Osteosarcoma-induction related to skeletal dose is discussed and compared with results of 226Ra known from the literature.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Quellenangaben
Volume: 20,
Issue: 1,
Pages: 27-38
Publisher
Informa Healthcare
Reviewing status
Peer reviewed
Institute(s)
Institut für Biologie