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Radiation induced heart disease in hypertensive rats.
Int. J. Radiat. Oncol. Biol. Phys. 14, 109-114 (1988)
Spontaneously hypertensive Wistar rats were given single doses of X rays to their heart. Irradiation decreased the blood pressure before any myocardial radiation damage was apparent. Male rats, which were more hypertensive than female rats, had a shorter survival time after local heart irradiation than female rats. Antihypertensive treatment with hydralazine did not increase the survival time. It is considered that myocardial hypertrophy is the cause of the increased susceptibility of spontaneously hypertensive rats to local heart irradiation.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Radiation-induced heart disease; Hypertension
Language
english
Publication Year
1988
HGF-reported in Year
0
ISSN (print) / ISBN
0360-3016
e-ISSN
0360-3016
Quellenangaben
Volume: 14,
Issue: 1,
Pages: 109-114
Publisher
Elsevier
Reviewing status
Peer reviewed
Institute(s)
Abteilung für Strahlenbiologie und Biophysik
PubMed ID
3335446
Scopus ID
0023858960
Erfassungsdatum
1988-01-30