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Radiation induced heart disease in hypertensive rats.

Int. J. Radiat. Oncol. Biol. Phys. 14, 109-114 (1988)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Spontaneously hypertensive Wistar rats were given single doses of X rays to their heart. Irradiation decreased the blood pressure before any myocardial radiation damage was apparent. Male rats, which were more hypertensive than female rats, had a shorter survival time after local heart irradiation than female rats. Antihypertensive treatment with hydralazine did not increase the survival time. It is considered that myocardial hypertrophy is the cause of the increased susceptibility of spontaneously hypertensive rats to local heart irradiation.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Radiation-induced heart disease; Hypertension
ISSN (print) / ISBN 0360-3016
e-ISSN 0360-3016
Quellenangaben Volume: 14, Issue: 1, Pages: 109-114 Article Number: , Supplement: ,
Publisher Elsevier
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Abteilung für Strahlenbiologie und Biophysik