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The effect of sulfite on the yeast Saccharomyces cerevisiae.

Arch. Microbiol. 125, 89-95 (1980)
Publ. Version/Full Text DOI
fter a short period of tolerance, living cells of Saccharomyces cerevisiae were irreversibly damaged by low concentrations of sulfite. The length of the period of tolerance and the rate of the damaging effect depended on the concentration on sulfite, pH-value, temperature, the physiological state of the cells, and incubation time. Inhibitors of protein synthesis and mitochondrial ATP synthesis did not alter the deleterious effect of sulfite on living cells. Furthermore, cell damage leading to inhibition of colony formation occured under aerobic as well as under anaerobic conditions. Prior to cell inactivation sulfite induced the formation of respiratory deficient cells. The active agent was shown to be SO2.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Sulfur dioxide; Sulfite; Air polluting substances; Saccharomyces cerevisiae; Active agent of irreversible cell inactivation
ISSN (print) / ISBN 0003-9276
e-ISSN 1432-072X
Quellenangaben Volume: 125, Issue: 1-2, Pages: 89-95 Article Number: , Supplement: ,
Publisher Springer
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institut für Toxikologie und Biochemie