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Verzögerte Implantation und frühembryonale Keimschaden bei der Maus nach Applikation des PCB: 2,2'-Dichlorbiphenyl.
Delayed implantation and early developmental defects in the mouse caused by PCB: 2,2'-dichlorobiphenyl.
Arch. Toxicol. 40, 249-254 (1978)
Pregnant mice administered per os during the days 1-3 (plug day = day 0) post conception (p.c.) with 375 mg 2,2'-dichlorobiphenyl/kg/day revealed on day 18 p.c. increased number of resorptions and doses up from 500 mg/kg/day led to a substantial retardation of the prenatal development. Based on the investigations during the early development it is concluded, that retardation of the fetus is caused by a delayed implantation. It is assumed, that increased resorption is due to kyematopathies detected during the periimplantation period.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0340-5761
e-ISSN
1432-0738
Journal
Archives of Toxicology
Quellenangaben
Volume: 40,
Issue: 4,
Pages: 249-254
Publisher
Springer
Reviewing status
Peer reviewed
Institute(s)
Institut für Biologie