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Malik, J.K. ; Lay, J.P. ; Klein, W. ; Korte, F.

Elimination pattern and biodistribution of [14C]chlorferron in rats.

Toxicol. Lett. 7, 449-452 (1981)
DOI
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Administration of [14C]chlorferron in a single oral dose of 0.5 and 20 mg/kg body weight to female rats resulted in a urinary excretion of > 74% of the given dose during the first 24 h. Approx. 8% of the dose was eliminated in faeces within 7 days. 7 days after dosing, very low levels of [14C]chlorferron-derived residues were detected in all analyzed organs. These findings indicated that chlorferron was absorbed from the gastro-intestinal tract in appreciable quantities, but was rapidly excreted mainly via the urine with small amounts only in the faeces.
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 0378-4274
e-ISSN 1879-3169
Journal Toxicology Letters
Quellenangaben Volume: 7, Issue: 6, Pages: 449-452 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Reviewing status Peer reviewed
Institute(s) Institute of Ecological Chemistry (IOEC)