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Elimination pattern and biodistribution of [14C]chlorferron in rats.
Toxicol. Lett. 7, 449-452 (1981)
Administration of [14C]chlorferron in a single oral dose of 0.5 and 20 mg/kg body weight to female rats resulted in a urinary excretion of > 74% of the given dose during the first 24 h. Approx. 8% of the dose was eliminated in faeces within 7 days. 7 days after dosing, very low levels of [14C]chlorferron-derived residues were detected in all analyzed organs. These findings indicated that chlorferron was absorbed from the gastro-intestinal tract in appreciable quantities, but was rapidly excreted mainly via the urine with small amounts only in the faeces.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
1981
HGF-reported in Year
0
ISSN (print) / ISBN
0378-4274
e-ISSN
1879-3169
Journal
Toxicology Letters
Quellenangaben
Volume: 7,
Issue: 6,
Pages: 449-452
Publisher
Elsevier
Publishing Place
Amsterdam
Reviewing status
Peer reviewed
Institute(s)
Institute of Ecological Chemistry (IOEC)
Scopus ID
0019859730
Erfassungsdatum
1981-12-31