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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Fundamentals of laser light interaction with human tissue, especially in the cardiovascular system.
Thorac. Cardiovasc. Surg. 36, 118-125 (1988)
The absorption of single photons in the molecules of biological tissue can induce various reactions. For the most medical laser applications the transformation from radiation energy into heat is relevant. The laser beam is used for coagulation or vaporization of tissue. The changes in tissue, which are created by light of different wavelengths depends on the thermal and optical properties (absorption and scatting) of tissue but also on the parameters of irradiation. As an example measurements from human skin are discussed. In the cardiovascular system laser light must have a clearly defined effect. Atherosclerotic plaques of different consistence have to be vaporized without damage of the vessel walls. From different reasons the usual medical CW-lasers, Argon-laser, CO2-laser and Nd:YAG-laser, are not optimal for direct ablation of arterial occlusions. In order to minimize reocclusion the walls of the channels have to be completely smooth and free of coagulation necrosis. This can be obtained by short laser pulses.Selection of a light wavelength, which is stronger absorbed in atherosclerotic plaques than in vessel walls and additional selective staining are two ways to reduce the risk of damaging the vessel walls.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Human tissue; Thermal properties; Optical properties; Coagulation; Vaporization; CW laser; Pulse laser; Angioplasty; Plaques; Blood vessels walls; Hot tip
ISSN (print) / ISBN
0040-6384
e-ISSN
1439-1902
Quellenangaben
Volume: 36,
Pages: 118-125
Publisher
Thieme
Reviewing status
Peer reviewed
Institute(s)
Institut für angewandte Optik