PuSH - Publication Server of Helmholtz Zentrum München: Regulation of sterol biosynthesis in yeast: Induction of 3-hydroxy-3-methylglutaryl-CoA reductase by glucose.

Information

Clues to quality of journals

Open Access Policy of Helmholtz Association 2016

CC Licencences

Publication Metrics

Navigation

Home

Deutsch

EVA: Electronic Publishing

New EVA Application

Research

Advanced Search

Browse by ...

... HMGU-Authors/Consortia

... Organizational Structure

... Journal

... Publication Type

... Research Data

... Arbeitsgruppen

... Publication Year

Publication overview

Statistics

Statistics (last 5 years)

OA Publications

Publish

Submit Publication

Import publication from...

...EVA

Report missing publication

Highlights

Support & Contact

Contact persons

Help

Data protection

Helmholtz Open Science

JANE Journal Estimator

SHERPA/RoMEO

DOAJ

Export:

Text

Endnote (RIS) BIB

BibTeX

Berndt, J. ; Boll, M. ; Löwel, M. ; Gaumert, R.

Regulation of sterol biosynthesis in yeast: Induction of 3-hydroxy-3-methylglutaryl-CoA reductase by glucose.

Biochem. Biophys. Res. Commun. 51, 843-848 (1973)

DOI

Open Access Green as soon as Postprint is submitted to ZB.

Abstract
Metrics
Extra information

Anaerobically cultured yeast cells have a very low HMG-CoA reductase activity and a low sterol content. When these cells are transfered to phosphate buffer containing 1.2 % glucose and held under aerobic conditions, the specific activity of the HMG-CoA reductase increases up to sixfold within 8 hrs. The increase in the reductase activity is paralled by an increase in the sterol content. This induction of HMG-CoA reductase in resting yeast cells is inhibited by cycloheximide indicating that a de novo synthesis of enzyme protein is mediated by glucose under aerobic conditions. It appears that the regulation of sterol synthesis in yeast is closely connected with the aerobic glucose metabolism.

Impact Factor

Scopus SNIP

Altmetric

0.000