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Pohlit, W. ; Drenkard, S.

Quantitative determination of the contribution of indirect and direct radiation action to the production of lethal lesions in mammalian cells.

Radiat. Prot. Dosim. 13, 195-198 (1985)

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Open Access Green as soon as Postprint is submitted to ZB.

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For quantitative models of radiation action in living cells it is necessary to know what fraction of the absorbed dose affects the target molecule by direct radiation action and what fraction by indirect radiation action. Mammalian cells were irradiated in suspension, saturated with N2O or CO2. With these gases the production of OH-radicals is changed by a factor of two in aqueous solutions and a corresponding change in cell survival would be expected, if only indirect radiation action is involved in the production of lethal lesions in the living cell. No difference could be detected, however, and it is concluded that indirect radiation action does not contribute to radiation lethality in mammalian cells.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

ISSN (print) / ISBN 0144-8420

e-ISSN 1742-3406

Journal Radiation Protection Dosimetry

Quellenangaben Volume: 13, Issue: 1-4, Pages: 195-198

Publisher Oxford University Press

Publishing Place Oxford

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Departments & Institutes