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Chromosomenanalysen in Zellkulturen des chinesischen Hamsters nach Applikation von Bleiacetat.
Mutat. Res. -Fund. Mol. Mech. Mutag. 14, 95-100 (1972)
Chinese hamster cell cultures were treated with different concentrations of lead acetate for a period of one cell cycle. Afterwards chromosome damage and disturbance of the mitotic apparatus were investigated. With increasing lead acetate concentration the mitotic index decreased. However, structural chromosome aberrations, which can be related to true discontinuities of the chromosome structure, and disturbance of the chromosome distribution were never more frequent than in controls. On the other hand, the achromatic lesions of gaps increased with the most concentrated lead acetate solution.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0027-5107
e-ISSN
1873-135X
Quellenangaben
Volume: 14,
Issue: 1,
Pages: 95-100
Publisher
Elsevier
Reviewing status
Peer reviewed
Institute(s)
Institut für Biologie
Institut für Hämatologie
Institut für Hämatologie