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Chromosome aberrations in human lymphocytes induced by fission neutrons.

Int. J. Radiat. Biol. 45, 449-457 (1984)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
The dose-response relationships of dicentrics and excess acentrics were analysed after exposure of human lymphocytes to a mixed fission neutron-γray beam. From the analysis of exclusively first division cells a linear-quadratic relation was obtained for dicentrics with the ratio of linear and quadratic components, ζ equal to 2·76 Gy. Over the range of doses studied (0·04-1·97 Gy) intratrack events therefore predominated. This also applied to acentrics which were linearly related to dose. At the lowest level of observed effect and dose, r.b.e. values with respect to 60Co γrays of up to about 11 were derived for dicentrics and acentrics. With increasing neutron dose the r.b.e. decreased.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Chromosome Damge ; Dose-response Relationship ; Fission Neutrons ; Human Lymphocytes
ISSN (print) / ISBN 0955-3002
e-ISSN 1362-3095
Quellenangaben Volume: 45, Issue: 5, Pages: 449-457 Article Number: , Supplement: ,
Publisher Informa Healthcare
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Abteilung für Strahlenbiologie und Biophysik