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Hilscher, W.M.* ; Trott, K.R.

Cell progression and radiosensitivity of T1-prospermatogonia in wistar rats.

Int. J. Radiat. Biol. 41, 517-524 (1982)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
T1-prospermatogonia pass through a quiescent stage which lasts from before birth until day 4 after birth (p.n.). They progress into DNA synthesis and mitosis in two synchronous waves which are separated by 24 hours in the evenings of day 4 and 5. The first wave contains about 25 per cent of the total population, the second 75 per cent. The mean duration of S-phase is 10 hours, the mean duration of G2-phase is 4 hours. After irradiation, the capacity of T1-prospermatogonia to produce the normal number of proliferating and differentiating cells in the testes is reduced. During maturation, between day 21 post-conception (p.c.) and day 5 p.n. the radiosensitivity of T1-prospermatogonia decreases by a factor of over 5.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0955-3002
e-ISSN 1362-3095
Journal International Journal of Radiation Biology
Quellenangaben Volume: 41, Issue: 5, Pages: 517-524 Article Number: , Supplement: ,
Publisher Informa Healthcare
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Radiation Biology (ISB)