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Open Access Green as soon as Postprint is submitted to ZB.
Osteosarcoma induced by short-lived bone-seeking α emitters in mice: The role of age.
Environ. Res. 18, 101-114 (1979)
In three experiments with low, medium, and high osteosarcoma expectancy after incorporation of 224Ra or 227Th the osteosarcoma risk of adult (5-6 months old) female NMRI mice was compared with that of rapid growing (1 month old) animals. Similar to results in the literature with other bone-seeking radionuclides the age-corrected osteosarcoma incidence was not significantly different in both age groups. In the experiment with high osteosarcoma risk the time of tumor appearance was mainly determined by the time of start of the internal irradiation period. It seems that at lower osteosarcoma expectancy the time of appearance of the tumors is mainly determined by the age of the animals.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0013-9351
e-ISSN
1096-0953
Journal
Environmental Research
Quellenangaben
Volume: 18,
Issue: 1,
Pages: 101-114
Publisher
Elsevier
Publishing Place
San Diego, Calif.
Reviewing status
Peer reviewed
Institute(s)
Institut für Biologie