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A systematic review of quality and cost-effectiveness derived from Markov models evaluating smoking cessation interventions in patients with chronic obstructive pulmonary disease.
Expert Rev. Pharmacoecon. Outcomes Res. 15, 301-316 (2015)
Smoking cessation is the only strategy that has shown a lasting reduction in the decline of lung function in patients with chronic obstructive pulmonary disease. This study aims to evaluate the cost-effectiveness of smoking cessation interventions in patients with chronic obstructive pulmonary disease, to assess the quality of the Markov models and to estimate the consequences of model structure and input data on cost-effectiveness. A systematic literature search was conducted in PubMed, Embase, BusinessSourceComplete and Econlit on June 11, 2014. Data were extracted, and costs were inflated. Model quality was evaluated by a quality appraisal, and results were interpreted. Ten studies met the inclusion criteria. The results varied widely from cost savings to additional costs of €17,004 per quality adjusted life year. The models scored best in the category structure, followed by data and consistency. The quality of the models seems to rise over time, and regarding the results there is no economic reason to refuse the reimbursement of any smoking cessation intervention.
Impact Factor
Scopus SNIP
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Times Cited
Times Cited
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Cited By
Cited By
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1.669
0.788
9
10
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Publication type
Article: Journal article
Document type
Review
Keywords
Markov Model ; Chronic Obstructive Pulmonary Disease ; Cost–effectiveness ; Review ; Smoking Cessation; Health Technology-assessment; Dynamic Population-model; Economic-evaluation; Lung Health; Copd; Varenicline; Simulation; Guidelines; Countries; Germany
Language
english
Publication Year
2015
HGF-reported in Year
2015
ISSN (print) / ISBN
1473-7167
e-ISSN
1744-8379
Quellenangaben
Volume: 15,
Issue: 2,
Pages: 301-316
Publisher
Taylor & Francis
Publishing Place
London
Reviewing status
Peer reviewed
Institute(s)
Institute of Health Economics and Health Care Management (IGM)
German Center for Lung Research (DZL)
German Center for Lung Research (DZL)
POF-Topic(s)
30202 - Environmental Health
80000 - German Center for Lung Research
80000 - German Center for Lung Research
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-505300-002
G-501800-531
G-501800-531
PubMed ID
25600470
WOS ID
WOS:000351236700012
Erfassungsdatum
2015-01-29