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Open Access Green as soon as Postprint is submitted to ZB.
Mechanisms of neutrophil transendothelial migration.
Front. Biosci. 14, 1596-1605 (2009)
Neutrophil recruitment is an integral part of the immune response to infection as well as of inflammatory disorders. The process of neutrophil extravasation comprises a complex multistep cascade that is orchestrated by a tightly coordinated sequence of adhesive interactions with vessel wall endothelial cells. Adhesion receptors as well as signaling molecules in both neutrophils and endothelial cells regulate the recruitment of neutrophils into the site of inflammation or infection. The present review will focus on novel aspects with regards to the last step of neutrophil recruitment, namely the transmigration of neutrophils through endothelial cells.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2009
HGF-reported in Year
0
ISSN (print) / ISBN
1093-9946
e-ISSN
1093-4715
Journal
Frontiers in Bioscience
Quellenangaben
Volume: 14,
Pages: 1596-1605
Publisher
Frontiers
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
19273149
DOI
10.2741/3327
Erfassungsdatum
2009-12-31