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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Current aspects in the pathophysiology and treatment of chronic wounds in diabetes mellitus.
Biomed Res. Int. 2013:385641 (2013)
Impaired wound healing is a frequent and very severe problem in patients with diabetes mellitus, yet little is known about the underlying pathomechanisms. In this paper we review the biology of wound healing with particular attention to the pathophysiology of chronic wounds in diabetic patients. The standard treatment of diabetic ulcers includes measures to optimize glycemic control as well as extensive debridement, infection elimination by antibiotic therapy based on wound pathogen cultures, the use of moisture dressings, and offloading high pressure from the wound bed. In this paper we discuss novel adjuvant therapies with particular reference to the use of autologous skin transplants for the treatment of diabetic foot ulcers which do not respond to standard care.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
2314-6133
e-ISSN
2314-6141
Journal
BioMed Research International
Quellenangaben
Volume: 2013,
Article Number: 385641
Publisher
Hindawi
Publishing Place
[New York, NY] [u.a.]
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)