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Fuertes, E. ; Standl, M. ; von Berg, A.* ; Lehmann, I.* ; Hoffman, B.* ; Bauer, C.P.* ; Koletzko, S.* ; Berdel, D.* ; Heinrich, J.

Parental allergic disease before and after child birth poses similar risk for childhood allergies.

Allergy 70, 873-876 (2015)
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Whether the strength of associations between parental and child allergic diseases differs by whether the first onset of the parental disease is before or after a child's birth has never been examined and is the aim of this study. Yearly childhood asthma, allergic rhinitis and eczema diagnoses were longitudinally regressed against the effect of a parental disease (pre versus post child birth) of the same type separately for each parent using generalized estimation equations. Both a maternal and paternal history of asthma were associated with childhood asthma prevalence up to 15 years of age. Effect estimates were similar for parental asthma with first onset before and after the birth of the child. The results for allergic rhinitis and eczema were less consistent. Parental allergic diseases with first onsets before and after the birth of a child both pose risks to childhood allergic disease in the offspring, especially for asthma.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Asthma ; Cohort ; Eczema ; Family History ; Rhinitis; Atopic-dermatitis; Giniplus; Eczema; Cohort; Impact
Language english
Publication Year 2015
HGF-reported in Year 2015
ISSN (print) / ISBN 0105-4538
e-ISSN 1398-9995
Journal Allergy
Quellenangaben Volume: 70, Issue: 7, Pages: 873-876 Article Number: , Supplement: ,
Publisher Wiley
Publishing Place Hoboken
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
POF-Topic(s) 30503 - Chronic Diseases of the Lung and Allergies
Research field(s) Genetics and Epidemiology
PSP Element(s) G-503900-001
PubMed ID 25764914
DOI 10.1111/all.12609
WOS ID WOS:000356366600015
Scopus ID 84931086154
Erfassungsdatum 2015-03-16
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