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Bigert, C.* ; Gustavsson, P.* ; Straif, K.* ; Pesch, B.* ; Brüning, T* ; Kendzia, B.* ; Schüz, J.* ; Stücker, I.* ; Guida, F.* ; Brüske, I. ; Wichmann, H.-E. ; Pesatori, A.C.* ; Landi, M.T.* ; Caporaso, N.* ; Tse, L.A.* ; Yu, I.T.* ; Siemiatycki, J.* ; Pintos, J.* ; Merletti, F.* ; Mirabelli, D.* ; Simonato, L.* ; Jöckel, K.-H.* ; Ahrens, W.* ; Pohlabeln, H.* ; Tardón, A.* ; Zaridze, D.* ; Field, J.* ; 't Mannetje, A.* ; Pearce, N.* ; McLaughlin, J.* ; Demers, P.* ; Szeszenia-Dabrowska, N.* ; Lissowska, J.* ; Rudnai, P.* ; Fabianova, E.* ; Stanescu Dumitru, R.* ; Bencko, V.* ; Foretova, L.* ; Janout, V.* ; Boffetta, P.* ; Forastiere, F.* ; Bueno-de-Mesquita, H.B.* ; Peters, S.* ; Vermeulen, R.* ; Kromhout, H.* ; Olsson, A.C.*

Lung cancer risk among cooks when accounting for tobacco smoking: S pooled analysis of case-control studies from Europe, Canada, New Zealand, and China.

J. Occup. Environ. Med. 57, 202-209 (2015)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
OBJECTIVES: To investigate the risk of lung cancer among cooks, while controlling for smoking habits. METHODS: We used data from the SYNERGY project including pooled information on lifetime work histories and smoking habits from 16 case-control studies conducted in Europe, Canada, New Zealand, and China. RESULTS: Before adjustment for smoking, we observed an increased risk of lung cancer in male cooks, but not in female cooks. After adjusting, there was no increased risk and no significant exposure-response relationship. Nevertheless, subgroup analyses highlighted some possible excess risks of squamous cell carcinoma and small cell carcinoma in female cooks. CONCLUSIONS: There is evidence that lung cancer risks among cooks may be confounded by smoking. After adjustment, cooks did not experience an increased risk of lung cancer overall. The subgroup analyses showing some excess risks among female cooks require cautious interpretation.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Aromatic-hydrocarbons Pahs; Dna-repair Genes; Mutagenic Aldehydes; Particulate Matter; Occupational-exposure; Nonsmoking Women; Case-referent; Population; Men; Mortality
ISSN (print) / ISBN 1076-2752
e-ISSN 1536-5948
Quellenangaben Volume: 57, Issue: 2, Pages: 202-209 Article Number: , Supplement: ,
Publisher Lippincott Williams & Wilkins
Publishing Place Philadelphia
Non-patent literature Publications
Reviewing status Peer reviewed