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as soon as is submitted to ZB.
Immunogenicity of embryonic stem cells and their progeny.
Methods Enzymol. 420, 391-409 (2006)
The ability of pluripotent human embryonic stem cells (hESCs) to differentiate into multiple cell types has led to great excitement about their potential use in the treatment of various degenerative and malignant human diseases. Before such a goal is attainable, however, it must be demonstrated that pure populations of specialized cell types can be isolated and transplanted while simultaneously avoiding possible immune-mediated rejection of these cells. In this chapter, I will discuss the utility of the humanized mouse Trimera model as an in vivo experimental system to study the immunological properties of hESCs and their differentiated derivatives.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2006
HGF-reported in Year
0
ISSN (print) / ISBN
0076-6879
e-ISSN
0076-6879
Journal
Methods in Enzymology
Quellenangaben
Volume: 420,
Pages: 391-409
Publisher
Elsevier
Reviewing status
Peer reviewed
Institute(s)
Institute of Stem Cell Research (ISF)
POF-Topic(s)
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Research field(s)
Stem Cell and Neuroscience
PSP Element(s)
G-552400-001
PubMed ID
17161708
Erfassungsdatum
2006-12-31