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Open Access Green as soon as Postprint is submitted to ZB.
Th22-Zellen bei allergischen Erkrankungen.
Allergo J. 24, 17-23 (2015)
During the last decade, the field of T cell immunology started to confuse the scientific community. More and more subtypes of T helper cells and their counterparts in the innate immune system are described. We are just at the beginning to understand which specific function the distinct subtypes fulfill. Th22 cells are terminally differentiated and very specialized T helper cells characterized by the secretion of their signature cytokine IL-22 and lack of IL-4, IL-17 and IFN-γ. The main function of Th22 cells is to protect epithelial barrier organs such as skin and lung, but also to modulate inflamed and injured tissue. This review summarizes our current knowledge on Th22 cells and their function in allergic disease. Cite this as Eyerich K, Eyerich S. Th22 cells in allergic disease. Allergo J Int 2015;24:1-7 DOI: 10.1007/s40629-015-0039-3.
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Publication type
Article: Journal article
Document type
Review
Keywords
Allergie ; Atopisches Ekzem ; Helferzelle ; Il-22 ; T-zelle ; Th22
ISSN (print) / ISBN
2195-6405
e-ISSN
0941-8849
Journal
Allergo Journal
Quellenangaben
Volume: 24,
Issue: 1,
Pages: 17-23
Publisher
Urban & Vogel
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute for Allergy Research (IAF)