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Segmentation and specification in the branchial region of the head: The role of the Hox selector genes.
Int. J. Dev. Biol. 42, 393-401 (1998)
Hox genes are segmentally expressed in the developing vertebrate hindbrain, neural crest cells and pharyngeal arches suggesting an important role in patterning these structures. Here we discuss the cellular and molecular mechanisms controlling segmentation and specification in the branchial region of the head. In addition, based on the recent phenotypical and molecular analysis of loss-of-function mutants in the mouse, we speculate that Hox genes may act like Drosophila selector genes in this system.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
1998
HGF-reported in Year
0
ISSN (print) / ISBN
0214-6282
e-ISSN
1696-3547
Quellenangaben
Volume: 42,
Issue: 3,
Pages: 393-401
Publisher
University of the Basque Country Press (UBC Press)
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
POF-Topic(s)
90000 - German Center for Diabetes Research
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-502600-003
PubMed ID
9654024
Erfassungsdatum
1998-12-31