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Taruttis, A. ; van Dam, G.M.* ; Ntziachristos, V.

Mesoscopic and macroscopic optoacoustic imaging of cancer.

Cancer Res. 75, 1548-1559 (2015)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Optoacoustic imaging combines the rich contrast of optical methods with the resolution of ultrasound imaging. It can therefore deliver optical visualization of cancer far deeper in tissue than optical microscopy and other conventional optical imaging methods. Technological progress and novel contrast media have resulted in optoacoustic imaging being propagated to basic cancer research and in clinical translation projects. We briefly review recent technological advances, showcase the ability to resolve unique cancer biomarkers based on spectral features at different imaging scales, and highlight the imaging performance achieved in preclinical and clinical imaging applications.
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Publication type Article: Journal article
Document type Review
Keywords Sentinel Lymph-nodes; In-vivo; Contrast Agents; Photoacoustic Microscopy; Breast-cancer; Ultrasonic Endoscopy; Indocyanine Green; Gold Nanorods; Rat Model; Tomography
ISSN (print) / ISBN 0008-5472
e-ISSN 1538-7445
Journal Cancer Research
Quellenangaben Volume: 75, Issue: 8, Pages: 1548-1559 Article Number: , Supplement: ,
Publisher American Association for Cancer Research (AACR)
Publishing Place Philadelphia, Pa.
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)