PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Volaklis, K.A.* ; Halle, M.R.* ; Meisinger, C.

Muscular strength as a strong predictor of mortality: A narrative review.

Eur. J. Intern. Med. 26, 303-310 (2015)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Muscular strength, an important component of physical fitness, has an independent role in the prevention of chronic diseases whereas muscular weakness is strongly related to functional limitations and physical disability. Our purpose was to investigate the role of muscular strength as a predictor of mortality in health and disease. We conducted a systematic search in EMBASE and MEDLINE (1980-2014) looking for the association between muscular strength and mortality risk (all-cause and cause-specific mortality). Selected publications included 23 papers (15 epidemiological and 8 clinical studies). Muscular strength was inversely and independently associated with all-cause mortality even after adjusting for several confounders including the levels of physical activity or even cardiorespiratory fitness. The same pattern was observed for cardiovascular mortality; however more research is needed due to the few available data. The existed studies failed to show that low muscular strength is predictive of cancer mortality. Furthermore, a strong and inverse association of muscular strength with all-cause mortality has also been confirmed in several clinical populations such as cardiovascular disease, peripheral artery disease, cancer, renal failure, chronic obstructive pulmonary disease, rheumatoid arthritis and patients with critical illness. However, future studies are needed to further establish the current evidence and to explore the exact independent mechanisms of muscular strength in relation to mortality. Muscular strength as a modifiable risk factor would be of great interest from a public health perspective.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
2.891
1.335
118
136
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Review
Keywords Disease ; Epidemiology ; Health ; Mortality ; Muscular Strength ; Risk Factor; All-cause Mortality; Peripheral Arterial-disease; American-heart-association; Skeletal-muscle Mass; Hand Grip Strength; Length-of-stay; Physical-activity; Cardiovascular-disease; Cardiorespiratory Fitness; Resistance Exercise
Language english
Publication Year 2015
HGF-reported in Year 2015
ISSN (print) / ISBN 0953-6205
e-ISSN 1879-0828
Journal European Journal of Internal Medicine
Quellenangaben Volume: 26, Issue: 5, Pages: 303-310 Article Number: , Supplement: ,
Publisher Pozzi
Publishing Place Roma
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
POF-Topic(s) 30202 - Environmental Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-504000-006
PubMed ID 25921473
DOI 10.1016/j.ejim.2015.04.013
WOS ID WOS:000354577000002
Scopus ID 84929512684
Scopus ID 84928200141
Erfassungsdatum 2015-04-30
[➜Report correction]