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Open Access Green as soon as Postprint is submitted to ZB.
RNA interference-based strategies for metabolic syndrome treatment.
Horm. Metab. Res. 37, 59-62 (2005)
RNA interference is a naturally occurring cellular mechanism to inhibit the expression of specific gene products. The technical application of RNA interference offers great potential for the specific treatment of a huge variety of diseases including the metabolic syndrome, one of the most challenging threats to human health associated with our civilization. In order to develop novel and powerful strategies for the treatment of the metabolic syndrome, it is essential to define a set of specific gene products that may be targeted by RNA interference. Based on currently available in vitro and in vivo data, we discuss the feasibility of candidate genes involved in the pathophysiology of the metabolic syndrome as potential targets for a rational RNA interference based therapy in this review.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2005
HGF-reported in Year
0
ISSN (print) / ISBN
0018-5043
e-ISSN
1439-4286
Journal
Hormone and Metabolic Research
Quellenangaben
Volume: 37,
Issue: 2,
Pages: 59-62
Publisher
Thieme
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
15778919
Erfassungsdatum
2005-12-31