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Mandal, S. ; Nasonova, E.* ; Dean-Ben, X.L. ; Razansky, D.

Fast calibration of speed-of-sound using temperature prior in whole-body small animal optoacoustic imaging.

Proc. SPIE 9323:93232Q (2015)

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The speed of sound (SoS) in the imaged sample and in the coupling medium is an important parameter in optoacoustic tomography that must be specified in order to accurately restore maps of local optical absorbance. In this work, several hybrid focusing functions are described that successfully determine the most suitable SoS based on post-reconstruction images. The SoS in the coupling medium (water) can be determined from temperature readings. Thereby, this value is suggested to be used as an initial guess for faster SoS calibration in the reconstruction of tissues having a different SoS than water.

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