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Cardiovascular disease mortality of a-bomb survivors and the healthy survivor selection effect.
Radiat. Prot. Dosim. 166, 320-323 (2015)
The latest A-bomb survivor data for cardiovascular diseases are analysed to investigate whether in the first years after the bombings the baseline rates of proximal survivors were markedly different compared with those of the distal survivors. This phenomenon relates to a healthy survivor selection effect. This question is important for the decision whether to include or exclude the early years of follow-up when analysing the biological effects from acute low and high dose exposures following the nuclear weapons explosions in Hiroshima and Nagasaki. The present study shows that for cerebrovascular diseases and heart diseases the baseline rates are not significantly different in the first two decades of follow-up. Thus, for these two detrimental health outcomes, there is no need to exclude distal survivors and the first decades of follow-up time when investigating the shapes of the related dose-responses.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2015
HGF-reported in Year
2015
ISSN (print) / ISBN
0144-8420
e-ISSN
1742-3406
Journal
Radiation Protection Dosimetry
Quellenangaben
Volume: 166,
Issue: 1-4,
Pages: 320-323
Publisher
Oxford University Press
Publishing Place
Oxford
Reviewing status
Peer reviewed
POF-Topic(s)
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Research field(s)
Radiation Sciences
Enabling and Novel Technologies
Enabling and Novel Technologies
PSP Element(s)
G-501100-004
G-500300-001
G-501100-005
G-500300-001
G-501100-005
PubMed ID
25948837
WOS ID
WOS:000361806600065
Scopus ID
84941753181
Erfassungsdatum
2015-05-09