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O'Dushlaine, C.* ; McQuillan, R.* ; Weale, M.E.* ; Crouch, D.J.M.* ; Johansson, A.* ; Aulchenko, Y.* ; Franklin, C.S.* ; Polasek, O.* ; Fuchsberger, C.* ; Corvin, A.* ; Hicks, A.A.* ; Vitart, V.* ; Hayward, C.* ; Wild, S.H.* ; Meitinger, T. ; van Duijn, C.M.* ; Gyllensten, U.* ; Wright, A.F.* ; Campbell, H.* ; Pramstaller, P.P.* ; Rudan, I.* ; Wilson, J.F.*

Genes predict village of origin in rural Europe.

Eur. J. Hum. Genet. 18, 1269-1270 (2010)
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Open Access Green as soon as Postprint is submitted to ZB.
The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.
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Publication type Article: Journal article
Document type Scientific Article
Keywords population structure; principal components; genome-wide genotyping; populations
Language english
Publication Year 2010
HGF-reported in Year 2010
ISSN (print) / ISBN 1018-4813
e-ISSN 1476-5438
Journal European Journal of Human Genetics
Quellenangaben Volume: 18, Issue: 11, Pages: 1269-1270 Article Number: , Supplement: ,
Publisher Nature Publishing Group
Publishing Place London
Reviewing status Peer reviewed
Institute(s) Institute of Human Genetics (IHG)
POF-Topic(s) 30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-500700-001
DOI 10.1038/ejhg.2010.92
Scopus ID 77958470124
Erfassungsdatum 2010-12-06
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