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Mandal, S. ; Dean-Ben, X.L. ; Burton, N.C.* ; Razansky, D.

Extending biological imaging to the fifth dimension: Evolution of volumetric small animal multispectral optoacoustic tomography.

IEEE Pulse 6, 47-53 (2015)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Despite the ancient discovery of the basic physical phenomenon underlying optoacoustic imaging and tomography [1], the lack of suitable laser sources, ultrasound detection technology, data acquisition, and processing capacities has long hindered the realization of efficient imaging devices. In fact, the first high-quality images from living animals were obtained about a decade ago (Figure 1), which was followed by an exponential growth of technical developments in instrumentation, algorithms, and biomedical applications surrounding this fascinating field. The ability of optoacoustics to probe optical contrast along a wide domain of penetration scales while maintaining excellent spatiotemporal resolution representative of ultrasound imaging, as shown in Figure 2, is unparalleled among the other optical imaging modalities [2], [3].
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 2154-2287
Journal IEEE Pulse : A Magazine of the IEEE Engineering in Medicine and Biology Society
Quellenangaben Volume: 6, Issue: 3, Pages: 47-53 Article Number: , Supplement: ,
Publisher Institute of Electrical and Electronics Engineers (IEEE)
Publishing Place New York, NY
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)