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Open Access Green as soon as Postprint is submitted to ZB.
Epidemiology of air pollution and diabetes.
Trends Endocrinol. Metab. 26, 384-394 (2015)
Air pollution affects a large proportion of the global population. Air pollutants are hypothesized to exert their effects via impaired endothelial function, elevated systemic inflammation, mitochondrial dysfunction, and oxidative stress, all of which are hallmarks of type 2 diabetes (T2D). Here we review epidemiological studies aimed at answering whether diabetes patients are more vulnerable to ambient (outdoor) air pollution exposure and whether air pollution is associated with diabetes development or other predisposing conditions for T2D. Current evidence suggests an association between air pollution exposure and T2D, but more critical analysis is warranted. Understanding the associations between air pollution exposure and the development of T2D is critical in our efforts to control sources of air pollution and their impact on the disease.
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Publication type
Article: Journal article
Document type
Review
Keywords
Air Pollution ; Gestational Diabetes ; Mortality ; Type 2 Diabetes; Long-term Exposure; Fine Particulate Matter; Case-crossover Analysis; Insulin-resistance; Daily Mortality; Risk-factors; Cardiovascular-disease; Susceptibility Factors; Effect Modifiers; Lung-cancer
ISSN (print) / ISBN
1043-2760
e-ISSN
1879-3061
Quellenangaben
Volume: 26,
Issue: 7,
Pages: 384-394
Publisher
Elsevier
Publishing Place
London
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Epidemiology (EPI)