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Utilization of extended donor criteria in liver transplantation: A comprehensive review of the literature.
Nephrol. Dial. Transplant. 22, 29-36 (2007)
Organ shortage has driven many transplant programs to extend their criteria to accept donors. The goal of the present work is to further characterize the most important extended donor criteria (EDC) in liver transplantation and to identify factors that impact outcomes for this type of grafts through a comprehensive review of the most recent findings and current opinions. Age, steatosis, positive viral hepatitis serology, intensive care unit stay, and history of malignancy in donor have been the matter of substantial debate in recent years and are therefore discussed in further detail here. Cold and warm ischemic times have also been discussed separately as they have been identified as important independent risk factors for mortality. The use of grafts with EDC provides an immediate expansion of the donor pool. However, in order to optimize effective utilization of EDC, attempts should be made to carefully match the most appropriate graft-recipient pair.
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Publication type
Article: Journal article
Document type
Review
Language
english
Publication Year
2007
HGF-reported in Year
0
ISSN (print) / ISBN
0931-0509
e-ISSN
1460-2385
Quellenangaben
Volume: 22,
Pages: 29-36
Publisher
Oxford University Press
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
17890260
Erfassungsdatum
2007-12-31