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Koch, M.* ; Kienle, P.* ; Antolovic, D.* ; Büchler, M.W.* ; Weitz, J.*

Is the lateral lymph node compartment relevant?

Recent Results Cancer Res. 165, 40-45 (2005)
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Open Access Green as soon as Postprint is submitted to ZB.
Lateral pelvic lymphadenectomy is routinely performed in advanced lower rectal cancers by Japanese surgeons, whereas in the western world it has not progressed to a frequently performed technique. Claimed benefit for this extensive surgery is an improved locoregional control; on the other hand, low positive lateral lymph node yields, questionable prognostic significance, and high morbidity (urinary and sexual dysfunction) are main reasons against this procedure. Clinical results published on lateral lymphadenectomy in the literature are conflicting. Due to major improvements in local control and survival of rectal cancer patients mainly based on preoperative radiotherapy and total mesorectal excision (TME), only a few patients may profit from lateral lymph node dissection. This article gives an overview of the current status and the clinical relevance of the lateral lymph node compartment in rectal cancer surgery.
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Publication type Article: Journal article
Document type Review
Language english
Publication Year 2005
HGF-reported in Year 0
ISSN (print) / ISBN 0080-0015
Quellenangaben Volume: 165, Issue: , Pages: 40-45 Article Number: , Supplement: ,
Publisher Springer
Reviewing status Peer reviewed
Institute(s) Institute of Pancreatic Islet Research (IPI)
PubMed ID 15865019
Erfassungsdatum 2005-12-31