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von Knebel Doeberitz, M.* ; Weitz, J.* ; Koch, M.* ; Lacroix, J.* ; Schrödel, A.* ; Herfarth, C.*

Molecular tools in the detection of micrometastatic cancer cells - technical aspects and clinical relevance.

Recent Results Cancer Res. 158, 181-186 (2001)
PMC
Open Access Green as soon as Postprint is submitted to ZB.
The frequent failure to reduce the mortality due to epithelial cancers by common medical intervention results primarily from early dissemination of cancer cells, which is missed by conventional diagnostic procedures used for tumor staging. Individual carcinoma cells present in regional lymph nodes, blood or distant organs (e.g., bone marrow) can be detected by sensitive immunologic or molecular methods. Here, we review recently developed molecular assays for the detection of individual micrometastatic cancer cells and their clinical application in patients with epithelial tumors.
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Publication type Article: Journal article
Document type Review
Language english
Publication Year 2001
HGF-reported in Year 0
ISSN (print) / ISBN 0080-0015
Quellenangaben Volume: 158, Issue: , Pages: 181-186 Article Number: , Supplement: ,
Publisher Springer
Reviewing status Peer reviewed
Institute(s) Institute of Pancreatic Islet Research (IPI)
PubMed ID 11092045
Erfassungsdatum 2001-12-31