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Molecular tools in the detection of micrometastatic cancer cells - technical aspects and clinical relevance.
Recent Results Cancer Res. 158, 181-186 (2001)
The frequent failure to reduce the mortality due to epithelial cancers by common medical intervention results primarily from early dissemination of cancer cells, which is missed by conventional diagnostic procedures used for tumor staging. Individual carcinoma cells present in regional lymph nodes, blood or distant organs (e.g., bone marrow) can be detected by sensitive immunologic or molecular methods. Here, we review recently developed molecular assays for the detection of individual micrometastatic cancer cells and their clinical application in patients with epithelial tumors.
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Publication type
Article: Journal article
Document type
Review
Language
english
Publication Year
2001
HGF-reported in Year
0
ISSN (print) / ISBN
0080-0015
Quellenangaben
Volume: 158,
Pages: 181-186
Publisher
Springer
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
11092045
Erfassungsdatum
2001-12-31