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Open Access Green as soon as Postprint is submitted to ZB.
The state of the art of mammalian promoter recognition.
Brief. Bioinform. 4, 22-30 (2003)
The draft sequences of whole genomes are being published at an ever-increasing pace, thus providing access to the human genomic sequence and, more recently, the mouse sequence. Genomes of the invertebrates are also becoming available. Now that the genomic DNA of mammalian species is available, an old problem can be tackled with renewed vigour: mammalian promoter prediction. Gene promoters have proved elusive for more than a decade, despite their pivotal role in gene regulation. Recently, however, several new developments have made it possible to make meaningful large-scale predictions. This paper reviews the methods used for the prediction of mammalian, mostly human, promoters.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
promoter finding; promoter analysis; genome analysis
ISSN (print) / ISBN
1467-5463
e-ISSN
1477-4054
Journal
Briefings in Bioinformatics
Quellenangaben
Volume: 4,
Issue: 1,
Pages: 22-30
Publisher
Oxford University Press
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Experimental Genetics (IEG)