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Open Access Green as soon as Postprint is submitted to ZB.
Determination and analysis of cellular metabolic changes by noncanonical Hedgehog signaling.
Methods Mol. Biol. 1322, 187-198 (2015)
Hedgehog is a morphogen essential for body patterning and proper embryonic development from flies to humans. Thought quiescent in adults, its inappropriate reactivation is associated with many disparate genetic and sporadic types of human cancers. Recent findings have demonstrated a key, yet unexpected, role of the Hedgehog signaling pathway in metabolic control. Here, we describe a panel of methods to determine and analyze cellular and organismal metabolic changes downstream of the Hedgehog signaling pathway.
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Publication type
Article: Journal article
Document type
Scientific Article
Editors
Riobo, N.A.*
Keywords
Hedgehog; Metabolism; Glucose uptake; Calcium; Ampk
Language
english
Publication Year
2015
HGF-reported in Year
2015
ISSN (print) / ISBN
1064-3745
e-ISSN
1940-6029
Conference Title
Hedgehog Signaling Protocols
Journal
Methods in Molecular Biology
Quellenangaben
Volume: 1322,
Pages: 187-198
Publisher
Springer
Publishing Place
Berlin [u.a.]
Reviewing status
Peer reviewed
Institute(s)
Institute of Experimental Genetics (IEG)
POF-Topic(s)
90000 - German Center for Diabetes Research
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-501900-069
PubMed ID
26179049
Erfassungsdatum
2015-07-18