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Long-term effects of pergolide in the treatment of restless legs syndrome.
Neurology 56, 1399-1402 (2001)
An open follow-up of a controlled study in patients with restless legs syndrome (RLS) shows that the beneficial effect of pergolide on RLS symptoms persists throughout at least 1 year. Twenty-two patients of 28 (78.6%) continued to take pergolide. Polysomnographic measurements showed a persistent improvement of PLM index, PLMS arousal index, total sleep time, and sleep efficiency (p = 0.0001). Side effects, in particular nausea, were common but were well controlled by domperidone in most patients.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2001
HGF-reported in Year
0
ISSN (print) / ISBN
0028-3878
e-ISSN
1526-632X
Journal
Neurology
Quellenangaben
Volume: 56,
Issue: 10,
Pages: 1399-1402
Publisher
Lippincott Williams & Wilkins
Reviewing status
Peer reviewed
Institute(s)
Institute of Human Genetics (IHG)
POF-Topic(s)
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-500700-001
PubMed ID
11376198
Erfassungsdatum
2001-12-31