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Stiasny, K.* ; Wetter, T.C.* ; Winkelmann, J.* ; Brandenburg, U.* ; Penzel, T.* ; Rubin, M.* ; Hundemer, H.P.* ; Oertel, W.H.* ; Trenkwalder, C.*

Long-term effects of pergolide in the treatment of restless legs syndrome.

Neurology 56, 1399-1402 (2001)
PMC
Open Access Green as soon as Postprint is submitted to ZB.
An open follow-up of a controlled study in patients with restless legs syndrome (RLS) shows that the beneficial effect of pergolide on RLS symptoms persists throughout at least 1 year. Twenty-two patients of 28 (78.6%) continued to take pergolide. Polysomnographic measurements showed a persistent improvement of PLM index, PLMS arousal index, total sleep time, and sleep efficiency (p = 0.0001). Side effects, in particular nausea, were common but were well controlled by domperidone in most patients.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 2001
HGF-reported in Year 0
ISSN (print) / ISBN 0028-3878
e-ISSN 1526-632X
Journal Neurology
Quellenangaben Volume: 56, Issue: 10, Pages: 1399-1402 Article Number: , Supplement: ,
Publisher Lippincott Williams & Wilkins
Reviewing status Peer reviewed
POF-Topic(s) 30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-500700-001
PubMed ID 11376198
Erfassungsdatum 2001-12-31