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Ziegler-Heitbrock, L.

Blood monocytes and their subsets: Established features and open questions.

Front. Immunol. 6:423 (2015)
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In contrast to the past reliance on morphology, the identification and enumeration of blood monocytes are nowadays done with monoclonal antibodies and flow cytometry and this allows for subdivision into classical, intermediate, and non-classical monocytes. Using specific cell surface markers, dendritic cells in blood can be segregated from these monocytes. While in the past, changes in monocyte numbers as determined in standard hematology counters have not had any relevant clinical impact, the subset analysis now has uncovered informative changes that may be used in management of disease.
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Publication type Article: Journal article
Document type Review
Keywords Classical Monocytes ; Intermediate Monocytes ; Monocyte Subsets ; Nomenclature ; Non-classical Monocytes; Human Peripheral-blood; Human Dendritic Cells; Predict Cardiovascular Events; Cd14(+) Cd16(+) Monocytes; Gene-expression Profiles; Chronic Kidney-disease; Fc-epsilon-ri; Bone-marrow; Cd16-positive Monocytes; M-dc8(+) Monocytes
Language english
Publication Year 2015
HGF-reported in Year 2015
ISSN (print) / ISBN 1664-3224
e-ISSN 1664-3224
Journal Frontiers in Immunology
Quellenangaben Volume: 6, Issue: , Pages: , Article Number: 423 Supplement: ,
Publisher Frontiers
Publishing Place Lausanne
Reviewing status Peer reviewed
Institute(s) Institute of Lung Health and Immunity (LHI)
POF-Topic(s) 30503 - Chronic Diseases of the Lung and Allergies
Research field(s) Lung Research
PSP Element(s) G-501690-001
PubMed ID 26347746
DOI 10.3389/fimmu.2015.00423
WOS ID WOS:000360329100001
Scopus ID 84941286399
Erfassungsdatum 2015-09-10
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